史强强

一、个人简介

史强强，博士，副教授，九三学社社员。中国科学院昆明植物研究所博士，云南大学博士后。目前主要研究兴趣在于中药/天然药物特征性小分子结构和功能研究，以及基于天然产物的有机新物质创造和功能评价。迄今已从中药及天然药物中分离鉴定小分子次生代谢产物500余个，发现200多个新的天然产物。以第一作者或通讯作者，在 Natural Product Reports 、Organic Letters 、The Journal of Organic Chemistry 、Journal of Agricultural and Food Chemistry 等学术期刊，发表论文20余篇。

二、科研项目

1. 国家自然科学基金青年科学基金项目（2023-2025），主持

2. 西北农林科技大学引进人才启动经费（2021-2024），主持

三、研究领域

中药及天然药物次生代谢产物结构及功能研究、天然产物活性分子结构修饰、天然产物药物化学生物学

四、代表性学术论文

1. Shi, Qiang-Qiang; Tang, Jiang-Jiang*; Gao, Jin-Ming*, Picrotoxane sesquiterpenoids: chemistry, chemo- and bio-syntheses and biological activities. Natural Product Reports 2022 , 39 (11), 2096-2131. (IF：15.11，中科院一区)

2. Shi, Qiang-Qiang; Zhang, Xing-Jie; Wang, Ting-Ting; Wang, Qi; Sun, Tian-Tian; Amin, Muhammad; Zhang, Rui-Han; Li, Xiao-Li*; Xiao, Wei-Lie*, Euphopias A–C: three rearranged jatrophane diterpenoids with tricyclo[8.3.0.0^2,7]tridecane and tetracyclo[11.3.0.0^2,10.0^3,7] hexadecane cores from Euphorbia helioscopia . Organic Letters, 2020, 22 (20), 7820−7824. (IF：6.09，中科院一区)

3. Shi, Qiang-Qiang; Zhang, Yu; Wang, Ting-Ting†; Xiong, Feng; Zhang, Rui-Han; Li, Xiao-Li; Ji, Xu, Zhang, Xing-Jie*; Wang, Wei-Guang*; Xiao, Wei-Lie*, Euphopias D−F from Euphorbia L.: quantum chemical calculation-based structure elucidation and their bioactivity inhibiting NLRP3 inflammasome activation. Organic Chemistry Frontiers , 2021, 8, 3041−3046, (IF：5.16，中科院一区)

4. Shi, Qiang-Qiang; Lu, Shuang-Yang; Peng, Xing-Rong; Zhou, Lin; Qiu, Ming-Hua*, Hydroxynitrile glucosides: bioactive constituent recovery from the oil residue of Prinsepia utilis . Journal of Agricultural and Food Chemistry, 2021, 69 , 2438−2443. (IF：4.19，中科院一区)

5. Shi, Qiang-Qiang; Wang, Ting-Ting; Zhang, Xing-Jie†; Pu, Yu-Kun; Ji, Xu; Li, Xiao-Li*; Dai, Xiao-Chang; Zeb, Muhammad Aurang; Zhang, Rui-Han; Xiao, Wei-Lie*, The bioactive limonoids from Toona ciliate as NLRP3 inflammasome inhibitors. Industrial Crops and Products , 2021, 167 , 113533, (IF：4.24，中科院一区)

6. Shi, Qiang-Qiang; Zhang, Xing-Jie; Zhang, Yu; Wang, Qi; Amin, Muhammad; Li, Qing; Wu, Xue-Wen; Li, Xiao-Li*; Zhang, Rui-Han; Dai, Xiao-Chang; Xiao, Wei-Lie*, Toonaolides A–X, limonoids from Toona ciliata : Isolation, structural elucidation, and bioactivity against NLRP3 inflammasome. Bioorganic Chemistry, 2020, 105 , 104363. (IF：4.83，中科院二区)

7. Shi, Qiang-Qiang; Huang, Yan-Jie; Su, Hai-Guo; Gao, Ya; Lu, Shuang-Yang; Peng, Xing-Rong; Li, Xiao-Nian; Zhou, Lin; Qiu, Ming-Hua*, Structurally diverse lanostane triterpenoids from medicinal and edible mushroom Ganoderma resinaceum Boud. Bioorganic Chemistry, 2020, 100 , 103871. (IF：4.83，中科院二区)

8. Shi, Qiang-Qiang; Zhang, Xing-Jie; Wang, Ting-Ting†; Zhang, Yu; Zeb, Muhammad Aurang; Zhang, Rui-Han; Li, Xiao-Li*; Xiao, Wei-Lie*, Toonaones A−I, limonoids with NLRP3 inflammasome inhibitory activity from Toona ciliata M. Roem. Phytochemistry, 2021, 184 , 112661. (IF：3.04，中科院三区)

9. Shi, Qiang-Qiang; Huang, Yan-Jie; Su, Hai-Guo; Gao, Ya; Peng, Xing-Rong; Zhou, Lin; Li, Xiao-Nian; Qiu, Ming-Hua*, C-28 steroids from the fruiting bodies of Ganoderma resinaceum with potential anti-inflammatory activity. Phytochemistry, 2019, 168 . (IF：3.04，中科院三区)

10. Shi, Qiang-Qiang; Lu, Jing; Peng, Xing-Rong; Li, Da-Shan; Zhou, Lin; Qiu, Ming-Hua*, Cimitriteromones A–G, macromolecular triterpenoid-chromone hybrids from the rhizomes of Cimicifuga foetida . Journal of Organic Chemistry, 2018, 83 (17), 10359−10369. (IF：4.34，中科院二区)

五、联系方式

通讯地址：陕西杨凌西农路22号，西北农林科技大学化药与药学院

邮编：712100

邮箱：shiqiangqiang@nwafu.edu.cn;shiqq89@126.com

欢迎对天然产物感兴趣的研究生，本科生来实验室交流学习。